Evidence synthesis services matched to your question

One practice, every major synthesis design. We diagnose which method your question actually needs, then run it end to end to the standards your reviewers and committees expect.

4.9 / 5 across 1,194+ delivered projects

  • Cochrane and PRISMA 2020 methods
  • PhD methodologists
  • 100% human-written, no generative AI
  • Reproducible R and Stata code
  • Free quote within 24 hours
  • Mutual NDA on request

Evidence synthesis is the family of methods that identify, appraise, and combine the findings of multiple studies using explicit, reproducible procedures. The family includes the systematic review, meta-analysis, scoping review, rapid review, umbrella review, qualitative evidence synthesis, and the evidence and gap map. Our service is the practice that runs whichever of those designs fits your question, built to Cochrane and JBI methodology and reported to the PRISMA family of guidelines, with certainty rated by GRADE.

Matching the method to the question

The most consequential decision in any synthesis project is made before a single database is searched: which design answers the question you are actually asking. Commissioners often arrive requesting a systematic review when the question is really a mapping exercise, or a scoping review when the decision at stake needs a pooled effect estimate. Forcing the wrong design onto a question wastes months and produces a document reviewers will reject, so our first deliverable is a method recommendation with the reasoning written down. That diagnosis considers what the question is really asking, how mature the underlying literature is, what the decision deadline allows, and which audience will judge the result.

Your question looks likeThe right synthesis method
Does this intervention work, and how well?Systematic review, with meta-analysis where studies can be pooled
What evidence exists across this broad area?Scoping review or an evidence and gap map
Several systematic reviews already exist; what do they say together?Umbrella review of the existing reviews
We need a defensible answer before a fixed deadline in weeksRapid review with declared, transparent streamlining
How do people experience this intervention, and what are the barriers?Qualitative evidence synthesis
The evidence changes quickly and the answer must stay currentLiving systematic review with scheduled updates

Each row above is a design we run in-house. If your question points to a full systematic review, a pooled meta-analysis, a scoping review, a deadline-driven rapid review, an umbrella review of existing reviews, a synthesis of qualitative studies, or a living review that stays current, the same team carries it through, so nothing is lost in a handover between specialists.

Who commissions evidence synthesis

Organisations commission a synthesis when a decision has to survive scrutiny. The brief differs by commissioner, and we shape the design, the depth of appraisal, and the write-up to the audience that will judge it. Professional bodies and charities increasingly join this list, commissioning syntheses to underpin position statements and campaigns that opponents will pick apart.

Guideline developers

Syntheses built to feed a recommendation, with GRADE certainty ratings and evidence tables a panel can deliberate over rather than a narrative it has to take on trust.

Health technology assessment bodies

Reviews of clinical effectiveness structured for appraisal committees, with the search, selection, and analysis documented to the standard assessors audit against.

Government and policy teams

Evidence for programme and funding decisions, scoped to the policy window and reported so the method survives a challenge from any stakeholder.

Universities and research funders

Syntheses that anchor grant applications, doctoral programmes, and funded projects, and gap maps that show a funder where new primary research is genuinely needed.

What unites these commissioners is accountability. A guideline recommendation, a reimbursement decision, or a funding call built on a synthesis will eventually be challenged, and when that happens the synthesis itself is what gets audited. That is why every project we deliver is reproducible by design: the search can be rerun, the screening decisions can be traced, and the certainty ratings can be checked against the underlying studies. A synthesis that cannot be audited is an opinion with a bibliography.

The rigour standards behind every design

Whichever method fits, the standards underneath it do not change. Our reviews of intervention effects follow the Cochrane Handbook; scoping reviews, qualitative syntheses, and umbrella reviews follow the corresponding JBI manuals; and every project is reported to the appropriate member of the PRISMA family of guidelines, from the PRISMA 2020 statement for systematic reviews to its extensions for scoping reviews and searching. Where the question concerns effects, certainty is rated with GRADE, and our GRADE certainty-of-evidence service produces the evidence profiles a committee expects to see. Appraisal uses the tool the evidence demands, such as RoB 2 for randomised trials and ROBINS-I for non-randomised studies, applied by assessors who work with these instruments daily.

Standards are also the honest reason to commission carefully. A synthesis that skips appraisal, hides its search, or pools studies that should never be pooled is worse than no synthesis, because it lends false authority to a weak answer. We decline design choices that cannot be defended, and we say so at the scoping stage rather than after the invoice. The same discipline applies to timelines: we would rather narrow a question at the outset than deliver a broad one badly, and we tell you which trade-off you are making before you commit to it.

How delivery works

The process is deliberately front-loaded. Most of the decisions that determine whether a synthesis survives scrutiny are taken in the first stage, before any records are screened, which is why we put a senior methodologist on scoping rather than treating it as an administrative step. From there the work runs through the same disciplined sequence whatever the design, with progress reported in writing at each stage so you always know where the project stands and what has been decided.

  1. 1

    Scope and method match

    You send the question, the decision it serves, and the deadline. We diagnose the right design, define the eligibility logic, and return a written plan with a fixed quote.

  2. 2

    Protocol and search

    We draft a pre-specified protocol and run a documented, reproducible search across the databases and grey literature sources the design requires.

  3. 3

    Screening, extraction, and appraisal

    Records are screened against the criteria, data are extracted into structured tables, and every included study is appraised with the tool appropriate to its design.

  4. 4

    Synthesis and reporting

    We synthesise narratively, statistically, or thematically as the evidence allows, rate certainty where applicable, and write the manuscript to the relevant PRISMA guideline.

What you receive

Every engagement ends in a complete, defensible package rather than a summary document. The exact contents flex with the design, but the spine is constant: the protocol, the full search record, the selection flow, the appraisal, the synthesis, and a manuscript written for the audience that will judge it. If you are unsure which document type your organisation needs, our guide to the main types of literature review walks through the options in plain language.

  • A written method recommendation explaining why the chosen design fits your question
  • A pre-specified protocol with eligibility criteria and a planned synthesis approach
  • A documented, reproducible search strategy across the required databases and grey literature
  • Structured screening records, extraction tables, and study appraisal with the appropriate tool
  • A narrative, statistical, or thematic synthesis, with GRADE certainty ratings where the question concerns effects
  • A manuscript or report drafted to the applicable PRISMA guideline, ready for a journal, panel, or board

How scoping and fixed quotes work

We quote a fixed fee per project rather than by the hour, so the cost is known before any work begins. Behind the number sits the real analytical load: the design your question requires, the expected search yield, the number of outcomes, whether pooling or qualitative integration is involved, and how much of the writing you want us to draft. Send the question, the decision it has to inform, and your deadline, and a PhD methodologist will return a recommended design, a timeline, and a fixed quote with no obligation to proceed. If two designs could serve, we price both and explain the trade-off so the choice is yours. Everything from scoping to handover is done for you and delivered in writing, which keeps a precise record of every methodological decision for your files.

Frequently asked questions

What is evidence synthesis?
Evidence synthesis is the family of research methods that identify, select, appraise, and combine the results of multiple studies to answer a question with explicit, reproducible methods. Rather than relying on one study or an expert's impression, a synthesis gathers everything relevant, weighs its quality, and states what the body of evidence shows and how certain that finding is. Systematic reviews, meta-analyses, scoping reviews, rapid reviews, umbrella reviews, qualitative syntheses, and evidence and gap maps are all forms of evidence synthesis, each suited to a different kind of question.
What is the difference between evidence synthesis and a systematic review?
A systematic review is one type of evidence synthesis, not a synonym for it. Evidence synthesis is the umbrella term for any method that combines findings across studies using explicit, documented procedures. A systematic review is the best known member of that family: it answers a tightly specified question by searching comprehensively, screening against pre-specified criteria, appraising risk of bias, and synthesising the results. Other members, such as scoping reviews, rapid reviews, and umbrella reviews, keep the same discipline but serve different questions, so choosing among them is the first real decision in any project.
What are the different types of evidence synthesis?
The main types are the systematic review, which answers a focused question about effectiveness or association; the meta-analysis, which statistically pools comparable results; the scoping review, which maps what evidence exists across a broad area; the rapid review, which streamlines defined steps to deliver in weeks; the umbrella review, which synthesises existing systematic reviews; the qualitative evidence synthesis, which integrates findings from qualitative studies; and the evidence and gap map, which visualises where research is dense and where it is missing. Mixed-methods and living reviews combine or extend these designs.
How do I choose the right evidence synthesis method?
Start from the question, not the method. A focused question about whether an intervention works points to a systematic review, with meta-analysis if the studies are similar enough to pool. A broad question about what evidence exists points to a scoping review or an evidence and gap map. A question already covered by several systematic reviews points to an umbrella review. A decision with a hard deadline points to a rapid review, and questions about experience, acceptability, or barriers point to qualitative synthesis. We make this match at the scoping stage and explain the reasoning before any work begins.
How long does evidence synthesis take?
It depends almost entirely on the design. A full systematic review commonly needs nine to eighteen months from protocol to manuscript, and a meta-analysis sits inside that timeline. A rapid review is typically delivered in roughly four to twelve weeks because defined steps are streamlined and reported transparently. Scoping reviews and evidence maps usually fall between the two, driven by the breadth of the search yield. When we scope your project we confirm the deadline first and, if the question cannot be answered well in the available window, we recommend a design that can.
Why is evidence synthesis important for decision making?
Single studies conflict, and picking one to act on invites bias. Evidence synthesis matters because it assembles the whole relevant body of research, appraises how trustworthy each piece is, and states an overall finding with an honest rating of certainty. That is why guideline panels, health technology assessment bodies, and policy teams commission syntheses rather than citing individual trials: a documented, reproducible synthesis can be defended in front of a committee, updated as evidence accrues, and audited by anyone who questions the conclusion.

Send us your question and your deadline, and we will recommend the right synthesis method and return a fixed quote.

Free quote within 24 hours. 100% human-written by PhD methodologists.

Methodology reviewed by

Dr Eleanor Whitfield, PhD

Lead Review Methodologist

Leads protocol design, screening, and reporting across the practice, with a focus on reviews that survive editorial scrutiny.

Why researchers bring in a PhD methodologist

80+

systematic reviews are published every day (Hoffmann et al., 2021)

67.3 weeks

average time to complete a review in-house (Borah et al., BMJ Open 2017)

~70%

of published reviews rate critically low on AMSTAR 2 quality appraisal

4.9 / 5

our client rating across 1,194+ delivered projects